Ingredients: PediaVance Apple & Grape Flavors

PediaVance® is Made with Organic Ingredients

While the leading and store brands use artificial sweeteners, colors and flavors, PediaVance® only uses organic and natural ingredients. PediaVance® Oral Electrolyte is approximately 60% organic. Under the USDA organic laws, the minerals (electrolytes) used to prevent dehydration cannot be certified organic. This is because minerals are not agriculturally grown or harvested ingredients. Instead minerals are taken directly from the earth. No chemicals are used to extract or process the minerals. If the minerals could be certified organic, PediaVance® Oral Electrolyte would be considered 80% or greater organic by ingredient weight.

Apple PediaVance® Ingredients: Filtered Water, Organic White Grape Juice Concentrate, Organic Dextrose, Lactic Acid, Natural Flavor, Potassium Citrate, Sodium Chloride, Sodium Citrate, Stevia Leaf Extract, colored with Caramel Color, Zinc Gluconate.

Grape PediaVance® Ingredients: Filtered Water, Organic White Grape Juice Concentrate, Organic Dextrose, Lactic Acid, Natural Flavor, Fruit and Vegetable Juice for Color, Potassium Citrate, Sodium Chloride, Sodium Citrate, Stevia Leaf Extract, Zinc Gluconate.

PediaVance® is made without GMO ingredients. This product does not contain corn, gluten, preservatives or alcohol. It is certified kosher. No BPA used in packaging.

Carbohydrates

Brand Carbohydrate Source
Pediavance® Organic Dextrose,
Organic White Grape Juice Concentrate
Pedialyte® Dextrose
Generic Pediatric Electrolyte Solution
(i.e. CVS, Walgreens, Others)
Dextrose, Fructose

Carbohydrates are commonly referred to as sugars or starches; however, they are classified scientifically as monosaccharides, disaccharides, or polysaccharides. The carbohydrates used in PediaVance® Electrolyte are monosaccharides, which is a one molecule sugar. Examples are glucose (also sometimes called dextrose), fructose (sometimes called fruit sugar), and galactose. Glucose is the major fuel needed by the body for energy. It does not need to be broken down like more complex sugars. This is why intravenous fluids (IVs) used in medical situations contain glucose (dextrose). Dextrose can be injected directly into the bloodstream without the need for further digestion by the body and is a ready source of energy for the body’s cells.

Glucose is also used in oral electrolyte maintenance solutions, such as PediaVance®Electrolyte. A combination of sodium with glucose in the small intestine of the body promotes the absorption of water into the bloodstream, thus helping to keep the body hydrated. This physiological system in the body is referred to as the glucose-sodium cotransport system. So in diarrhea management, glucose is very important!

The organic white grape juice concentrate provides glucose and also a secondary source of carbohydrate called fructose or fruit sugar. Although the primary carbohydrate in PediaVance® is glucose to support the glucose-sodium co-transport system, small amounts of fructose have been shown over the years to be safe and effective. The naturally occurring fructose in organic white grape juice concentrate also works with the other flavor ingredients to make the solution tastier.

The balance of carbohydrates in a solution is also important in preventing or treating dehydration. Too much carbohydrate can cause the diarrhea to worsen by moving water from the body into the intestinal tract. PediaVance® Electrolyte is specifically designed to meet all of the requirements needed to maintain hydration in infants, children and adults. An appropriate combination in the proper amounts of organic dextrose and organic white grape juice is used to meet carbohydrate requirements.

Electrolytes

Brand Electrolyte Source
PediaVance® Potassium Citrate, Sodium Chloride,
Sodium Citrate
Pedialyte® Potassium Citrate, Sodium Chloride,
Sodium Citrate
Generic Pediatric Electrolyte Solution
(i.e. CVS, Walgreens, Others)
Potassium Citrate, Sodium Chloride,
Sodium Citrate

Sodium, potassium and chloride are called electrolytes. Electrolytes are mineral substances that become chemical ions in a solution and acquire the capacity to conduct electricity. The balance of the electrolytes in our bodies is essential for the normal functioning of body cells and organs. Electrolytes are needed to prevent dehydration that may be caused by diarrhea or vomiting from illnesses such as the flu, rotavirus, Norwalk virus or food poisoning. Giving pure water is not the best way to restore body fluid levels because it dilutes the minerals inside the body’s cells and interferes with their chemical and electrical functions.

The sources of electrolytes in PediaVance® Oral Electrolyte Solution are sodium chloride (to meet sodium and chloride needs), potassium citrate (to meet potassium needs), and sodium citrate (to also help meet sodium needs). Sodium chloride is salt. Sodium citrate and potassium citrate are rapidly absorbed when given orally and help to make the urine less acidic preventing metabolic acidosis. The use of potassium citrate as a good source of potassium in oral rehydration solutions has been well documented.1

Potassium: This is an electrolyte and works with sodium to regulate the body’s waste balance, transmit nerve impulses, and regulate muscle contraction including the heart muscles. It is essential for metabolism and the release of insulin.
PediaVance® Electrolyte: 4.7 mEq Potassium per 8 fluid ounces

Sodium: The primary role of sodium in the body is to maintain fluid balance. Sodium works with potassium and chloride to conduct electrical currents in the body and keep tissue fluids in balance. Sodium in combination with glucose aids the absorption of water from the intestinal tract into the bloodstream and from the bloodstream into body cells. This helps to retain fluids in the body and prevent dehydration.
PediaVance® Electrolyte: 10.6 mEq Sodium per 8 fluid ounces

Chloride: This electrolyte helps to maintain fluid balance in the body and also is a component of the stomach juices (hydrochloric acid) needed for digestion of foods.
PediaVance® Electrolyte: 8.3 mEq Chloride per 8 fluid ounces

1. Islam, M.R., “Can potassium citrate replace sodium bicarbonate and potassium chloride of oral rehydration solutions,” Archives of Diseases in Childhood, 60: 852-855, 1985.

Lactic Acid

Lactic acid is used in a wide range of food products as a preservative, acid regulator, or flavoring agent. The role of lactic acid in PediaVance® is to make the beverage less tart and this contributes to the pleasant and delicious taste. The lactic acid is all-natural and is derived from dextrose.

Organic Dextrose

PediaVance® organic dextrose is used by the body as a ready source of glucose that is derived from organic tapioca. Organic dextrose is a simple sugar that is quickly digested and absorbed into the bloodstream to provide a quick supply of energy. PediaVance® Electrolyte uses organic dextrose in combination with sodium to promote water absorption into the bloodstream to help keep the body hydrated.

Osmolality

The movement of water and electrolytes and glucose across the intestinal tract and into the bloodstream is known as osmosis. Solutions with an osmolality lower than blood serum make effective oral electrolyte solutions. Blood serum has an osmolality in the rand of 275 to 295 mOsm/liter. PediaVance® Oral Electrolyte Solution has an osmolality of 270 and is most appropriate for rehydration. Liquids such as apple juice, pear juice, carbonated sodas, and sports drinks are not recommended as rehydration solutions for infants and children because their osmolality is too high and this may worsen the diarrhea. Also, these drinks do not contain the appropriate balance of electrolytes and carbohydrates needed by infants and children to prevent or treat dehydration.

PediaVance® Electrolyte: 270 mOsm/kg H2O per 8 fluid ounces

Sweeteners, Color, & Flavor

Brand Color Flavor Sweetener
PediaVance® Fruit and vegetable juice (grape flavor), Caramel
(apple flavor)
Natural Flavors Organic White Grape Juice Concentrate, Stevia leaf extract
Pedialyte® Red 40 & Blue 1
(grape flavor), Yellow 6
(fruit flavor)
Artificial grape flavor; Natural and artificial flavors Sucralose*, Acesulfame, Potassium**
Generic Pediatric Electrolyte Solution
(i.e. CVS, Walgreens, Others)
Red 40 & Blue 1
(grape flavor), Yellow 6
(fruit flavor)
Natural and artificial flavors Sucralose*, Acesulfame, Potassium**

 

PediaVance® Electrolyte is the only electrolyte solution that does not contain artificial sweeteners, colors or flavors:

Sweeteners & Flavor
The carbohydrates used in PediaVance® serve a dual purpose. First, the carbohydrates provide the sweetness needed to cover the off flavors of the minerals (electrolytes) used in all electrolyte solutions. Also, the carbohydrates work together with the sodium to move water out of the intestinal tract and into the body, thus promoting hydration. PediaVance® contains organic white grape juice and organic dextrose as its source of carbohydrate and sweetener. Other natural ingredients that aid in the flavoring of PediaVance® include lactic acid to add a pleasant but not too tart taste and stevia leaf extract to provide sweetness for a delicious taste acceptable to infants and children without the use of artificial sweeteners.

The leading brand Pedialyte® uses sucralose as its carbohydrate, which is an artificial sweetener sold under the Splenda® brand name. The various store branded electrolyte solutions use the artificial sweetener acesulfame potassium, which is sold under the brand name Sunett® or Sweet One®.

Grape Color
PediaVance® grape flavored electrolyte solution is colored with natural fruit and vegetable juices. No artificial coloring agents are used in this product.

Apple Color
PediaVance® apple flavored electrolyte solution is colored with natural caramel. The natural caramel coloring comes from heating brown sugar. Dairy, gluten or barley malt is not used in the caramel coloring. No artificial coloring agents are used in this product.

Pedialyte® is a registered trademark of Abbott Laboratories
*Splenda is a registered trademark of McNeil Nutritionals, LLC for the sweetener sucralose
**Sunett is a registered trademark of Nutrinova for the sweetener acesulfame K.
*** Sweet One is a registered trademark of Stadt Holdings Corporation for the sweetener acesulfame potassium.

Organic White Grape Juice

The organic white grape juice provides a secondary source of carbohydrate in the form of fructose, sometimes called fruit sugar. Organic white grape juice also provides some natural flavoring to the solution. White grape juice has been recommended as the first fruit juice to introduce to an infant or toddler.1 Furthermore, white grape juice has been found to be well tolerated in children recovering from diarrhea because it holds the right combination of carbohydrates without the presence of sorbitol.2 Sorbitol is a non-digestible carbohydrate found in pear and apple juice which helps to move water into the gastrointestinal tract. This is one reason why apple and pear juice are often recommended for the treatment of constipation. Sorbitol helps with stool elimination. However, sorbitol is not beneficial to the child suffering from diarrhea or vomiting.

1. Nobigrot, T. et al, “Carbohydrate absorption from one serving of fruit juice in young children: age and carbohydrate effects,” Journal of the American College of Nutrition (2) 16: 152-148, April, 1997.
2. Ribeiro, R. et al, “Incomplete carbohydrate absorption from fruit juice consumption after acute diarrhea,” Journal of Pediatrics (2) 139: 325-327, August, 2001.

Zinc

Zinc is an essential trace mineral needed by the body to maintain a healthy immune system, aid in wound healing, and support good growth. During an illness causing diarrhea in infant and children, the intestinal cells secrete electrolytes, primarily sodium, and water into the intestinal tract resulting in the loss of water and electrolytes in the watery stools. Zinc helps to protect the intestinal cells and promote the absorption of water and electrolytes resulting in a decrease in the duration and severity of diarrhea.

PediaVance® contains 0.93 milligrams of zinc per 4 fluid ounce serving (one Liquid Stick).

Stevia Leaf Extract

Stevia leaf extract is the term used in the United States for the natural constituents of the plant called Stevia rebaudiana Bertoni, often simply referred to as Stevia. In Europe, the Joint FAO/WHO Expert Committee on Food Additives (JECFA) adopted the term steviol glycosides for the family of substances in Stevia with sweetness properties.1 For products manufactured in European countries, steviol glycosides rather than stevia leaf extract may be noted on the ingredient panel of the product label. Stevia has been used for centuries as a sweetener for foods and beverages and is 250 to 300 times sweeter than sugar.

Stevia leaf extract is a natural non-caloric sweetener and is not part of the carbohydrate profile for an oral rehydration solution. Because taste is such an important feature in the acceptability of an oral rehydration solution, especially with children, stevia leaf extract sweetens the product without disrupting the important carbohydrate to sodium level required in an oral rehydration product. Stevia leaf extract in conjunction with organic white grape juice concentrate and natural flavors makes PediaVance® a pleasant flavored beverage for the prevention or treatment of mild to moderate dehydration.

1 WHO, 2000. Joint FAO/WHO Expert Committee on Food Additives. WHO Food Additive Series; 42. Safety evaluation of certain food additives. Stevioside.

 

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